缘于颈动脉夹层的头痛特征

目的 探讨缘于颈动脉夹层的头痛特征，以期正确识别有头痛症状的颈动脉夹层患者，及时进行 相关干预，减少继发于颈动脉夹层的危险并发症，以及防止进行具有潜在危险性的治疗措施和动作。      

Functionally navigated transcranial magnetic stimulation to evoke lingual pressure in stroke survivors with dysphagia and healthy adults: a proof of concept trial

ABSTRACT

Background

Post-stroke dysphagia is characterized by reduced corticolingual excitability and lingual pressure; however, it remains unknown if transcranial magnetic stimulation (TMS) directly facilitates lingual pressure generation.     

胃癌手术患者2338例临床病理特征分析

目的分析2 338例胃癌手术患者的临床病理特征。方法回顾性分析2 338例胃癌患者的临床资料。患者分为年龄≤40岁(A组)、41-65岁(B组)和>65岁(C组)三组,比较肿瘤部位、病理类型和临床分期。结果胃癌高发年龄41-65岁,男性比例高于女性。肿瘤多见于贲门胃底部(42.48%)。肿瘤以BormannⅡ型多见(75.44%),病理类型以腺癌为主(90.03%)。肿瘤分化程度以低分化为主(74.25%)。胃癌浸润深度以T3期主(64.6%)。淋巴结转移以N0、N1期为主(85.31%)。TNM分期以Ⅲ期为主(48.47%)。结论胃癌高发于41-65岁男性。胃癌病理分型以低分化腺癌最常见。确诊患者多为胃癌中晚期,胃癌早期诊断率有待提高。     

慢性精神分裂症患者合并肺部感染临床资料分析

目的：探讨慢性精神分裂症患者合并肺部感染的临床特征。方法对162例慢性精神分裂症合并肺部感染患者的临床资料进行回顾性分析。结果162例肺部感染者，其中节段性肺炎124例，慢性肺部感染38例。急性肺炎以中青年，精神病病程＜3 a居多，感染部位以右肺中叶和左肺舌叶为主，对症治疗后均痊愈；慢性感染以中老年多见，精神病病程＞3a，感染部位以两肺下叶、肺底及脊柱两旁慢性感染为主，对症治疗后痊愈率为71．1％，临床症状消失率为28．9％。结论精神分裂症患者合并肺部感染率较高，临床症状不典型，应制定有效的预防和控制对策，减少感染的发生。     

Tongue surface model can predict radiation tongue mucositis due to intensity-modulated radiation therapy for head and neck cancer

Acute radiation tongue mucositis has a profound effect on talking and eating. We examined whether the dose–volume histogram obtained from the tongue surface model correlates with mucositis severity, and whether it is useful for predicting acute radiation tongue mucositis in patients with head and neck cancer treated with intensity-modulated radiation therapy. Thirty-six patients who received intensity-modulated radiation therapy for head and neck cancer were analysed for acute radiation tongue mucositis according to the Common Terminology Criteria for Adverse Events, version 4.0, as well as the Radiation Therapy Oncology Group scoring systems. The corresponding high-dose locations in anatomical sub-regions in the tongue surface model and the development of high-grade acute radiation tongue mucositis were compared. The mucositis sites coincided with the high-dose anatomical sub-regions in the tongue surface model. There was a clear dose–response relationship between the mean dose to the tongue and the acute radiation tongue mucositis Radiation Therapy Oncology Group grade. According to the dose–volume histogram, patients receiving 16.0–73.0 Gy to the tongue were susceptible to grade 2–3 toxicity. The tongue surface model can predict the site and severity of acute radiation tongue mucositis. In future, radiation treatment plans ccould be optimized using this model.     

慢性萎缩性胃炎患者中医舌象特征研究＊

目的 探讨慢性萎缩性胃炎患者的舌象特点，分析胃粘膜病理学改变与中医舌象变化的相关性。方法 本研究运用舌象仪采集慢性萎缩性胃炎患者的舌象信息，采用病例对照研究方法比较不同病理阶段的胃病患者舌象客观参数和特征，描述舌象特征的变化趋势，分析慢性萎缩性胃炎患者较常见的舌象特征。结果 慢性萎缩性胃炎组的舌色参数R值和V值显著高于慢性非萎缩性胃炎组与胃癌组（P < 0.05）；慢性萎缩性胃炎组中舌质红的患者显著多于慢性非萎缩性胃炎组与胃癌组（P < 0.01）；慢性萎缩性胃炎组的舌苔厚薄指数和剥苔指数均显著低于慢性非萎缩性胃炎组与胃癌组（P < 0.01），慢性萎缩性胃炎组中舌苔厚的患者显著多于慢性非萎缩性胃炎组与胃癌组（P < 0.01）；结论 舌质红和舌苔厚是慢性萎缩性胃炎患者常见的舌象特征。     

Network connectivity predicts language processing in healthy adults

Brain imaging has been used to predict language skills during development and neuropathology but its accuracy in predicting language performance in healthy adults has been poorly investigated. To address this shortcoming, we studied the ability to predict reading accuracy and single‐word comprehension scores from rest‐ and task‐based functional magnetic resonance imaging (fMRI) datasets of 424 healthy adults. Using connectome‐based predictive modeling, we identified functional brain networks with >400 edges that predicted language scores and were reproducible in independent data sets. To simplify these complex models we identified the overlapping edges derived from the three task‐fMRI sessions (language, working memory, and motor tasks), and found 12 edges for reading recognition and 11 edges for vocabulary comprehension that accounted for 20% of the variance of these scores, both in the training sample and in the independent sample. The overlapping edges predominantly emanated from language areas within the frontoparietal and default‐mode networks, with a strong precuneus prominence. These findings identify a small subset of edges that accounted for a significant fraction of the variance in language performance that might serve as neuromarkers for neuromodulation interventions to improve language performance or for presurgical planning to minimize language impairments.